| Annotated protein: | Clathrin heavy chain 1. Gene symbol: CLTC. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q68FD5 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ CLTC |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic endocytic zone (GO:0098843) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Moron JA, et al. "Morphine administration alters the profile of hippocampal postsynaptic density-associated proteins: a proteomics study focusing on endocytic proteins" Mol Cell Proteomics. 2007 Jan;6(1):29-42 PMID:17028301 |
| Figure(s): | Table 1, Figure 3 |
| Annotation description: | Table 1. Clathrin heavy chain (CLTC) was detected in biochemically enriched PSD fractions by LC-MS/MS. Figure 3. Immunogold labeling of clathrin heavy chain in the mouse hippocampal CA1 region shows localization at the postsynaptic membrane, to the side of the spine and near the PSD. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy Mass-spectrometry Biochemical fractionation (generic) |
| Annotator(s): | Peter McPherson (ORCID:0000-0001-7806-5662) |
| Lab: | Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada |
| SynGO annotation ID: | 4606 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |