| Annotated protein: | Clathrin heavy chain 1. Gene symbol: CLTC. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q68FD5 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ CLTC |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic endocytic zone (GO:0098843) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Fukaya M, et al. "BRAG2a Mediates mGluR-Dependent AMPA Receptor Internalization at Excitatory Postsynapses through the Interaction with PSD-95 and Endophilin 3" J Neurosci. 2020 May 27;40(22):4277-4296 PMID:32341099 |
| Figure(s): | Figure 11 |
| Annotation description: | Figure 11 (S,T) shows clathrin localization at the postsynaptic membrane, to the side of the spine and near the PSD, using immunogold labeling in excitatory asymmetric synapses of the mouse hippocampal CA1 region. The antibody is specific to clathrin heavy chain |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Peter McPherson (ORCID:0000-0001-7806-5662) |
| Lab: | Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada |
| SynGO annotation ID: | 4605 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |