Annotated protein:Sorting nexin-27. Gene symbol: SNX27. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q3UHD6
antibody wiki:
SynGO gene info:SynGO data @ SNX27
Ontology domain:Cellular Component
SynGO term:postsynaptic early endosome (GO:0098842)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Loo LS, et al. "A role for sorting nexin 27 in AMPA receptor trafficking" Nat Commun. 2014;5:3176 PMID:24458027
Figure(s):Fig. 4A
Annotation description:Fig. 4A shows colocalization of SNX27 with early endosomes marked by Rab5 in postsynaptic puncta of hippocampal neurons (16 DIV).
Evidence tracking, Biological System:Cultured neurons
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Confocal
Annotator(s):Daniela Dieterich (ORCID:0000-0002-9880-1214)
Rainer Pielot (ORCID:0000-0002-9681-3318)
Karl-Heinz Smalla (ORCID:0000-0002-0269-0311)
Eckart Gundelfinger (ORCID:0000-0001-9377-7414)
Lab:Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany
SynGO annotation ID:4562
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology