| Annotated protein: | Microtubule-associated protein 2 (MAP-2). Gene symbol: MAP2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P15146 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ MAP2 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Morales M, et al. "Distribution of MAP2 in dendritic spines and its colocalization with actin. An immunogold electron-microscope study" Cell Tissue Res. 1989 Jun;256(3):447-56 PMID:2743390 |
| Figure(s): | Fig. 28 |
| Annotation description: | Fig. 28 shows the colocalization of MAP2 and actin on group of filaments (big arrow) associated with the PSD (small arrow). Both antigens also colocalized in PSD (arrowhead). Fig. 1 shows the specificity of the MAP2-antibody. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
| Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
| Additional literature: | Fig. 3B shows immunogold-labeling in hippocampal dendrites and an excitatory synapse in the mouse brain by anti-MAP2. @ PMID:19020041 |
| SynGO annotation ID: | 4514 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |