Annotated protein: | Dystrophin-related protein 2 (DRP-2). Gene symbol: DRP2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q9EPA0 |
antibody wiki: | |
SynGO gene info: | SynGO data @ DRP2 |
Ontology domain: | Cellular Component |
SynGO term: | postsynaptic density (GO:0014069) |
Synapse type(s): | brain, glutamatergic |
Annotated paper: | Roberts RG, et al. "Association of dystrophin-related protein 2 (DRP2) with postsynaptic densities in rat brain" Mol Cell Neurosci. 2000 Nov;16(5):674-85 PMID:11083927 |
Figure(s): | Fig. 4, Fig. 6 |
Annotation description: | Fig. 4: biochemical purification of postsynaptic density (PSD) fraction indicates that DRP2 is associated to PSD. Fig 6: Costaining of DRP2 and PSD-95 on brain slices indicates that DRP2 colocalize with PSD-95. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Confocal Western blot Biochemical fractionation (generic) |
Annotator(s): | Chiara Verpelli (ORCID:0000-0003-2949-9725) Carlo Sala (ORCID:0000-0003-0662-9523) |
Lab: | CNR Neuroscience Institute Milan and Dept. of Biotechnology and Translational Medicine, University of Milan, 20129 Milan, Italy |
SynGO annotation ID: | 427 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |