Annotated protein: | Small ribosomal subunit protein eS27 (40S ribosomal protein S27). Gene symbol: RPS27. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q71TY3 |
antibody wiki: | |
SynGO gene info: | SynGO data @ RPS27 |
Ontology domain: | Cellular Component |
SynGO term: | presynapse (GO:0098793) |
Synapse type(s): | brain, glutamatergic brain, GABAergic |
Annotated paper: | Boyken J, et al. "Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses" Neuron. 2013 Apr 24;78(2):285-97 PMID:23622064 |
Figure(s): | Suppl. Table S1 (mmc2.xlsx), S5 (mmc4.xlsx) |
Annotation description: | Average enrichment of 40S ribosomal protein S27 in docked synaptic vesicles vs. free vesicles is 4.1 fold (Table S1) and about 1.4 fold in VGLUT1 vs. VGAT positive terminals. 8/8/2017 Pim - Protein is considererd as a marker protein of ribosomes. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Mass-spectrometry Biochemical fractionation (generic) |
Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
SynGO annotation ID: | 414 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |