| Annotated protein: | Sorting nexin-14. Gene symbol: SNX14. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q8BHY8 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ SNX14 |
| Ontology domain: | Cellular Component |
| SynGO term: | synapse (GO:0045202) |
| Synapse type(s): | cerebral cortex |
| Annotated paper: | Huang HS, et al. "Snx14 regulates neuronal excitability, promotes synaptic transmission, and is imprinted in the brain of mice" PLoS One. 2014 May 23;9(5):e98383 PMID:24859318 |
| Figure(s): | Fig2 |
| Annotation description: | Fig2F: Immunocytochemistry demonstrates that Snx14 colocalises with dendritic marker MAP2 in dissociated mouse cortical neurons. Fig2E: Dissociated mouse cortical neurons were transfected with pZsGreen1-Snx14 plasmid and subsequently immunostained with mouse anti-SNX14 antibody and showed colocalisation with ZsGreen1. This indicates the specificity of the anti-SNX14 antibody. 18/01/2021 Dnyanada: The generic term "synapse" was used for this annotation as the paper only shows the presence of SNX14 puncta on dendrites. |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Dnyanada Sahasrabudhe (ORCID:0000-0003-2916-7616) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 4112 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |