Annotated protein: | Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2). Gene symbol: ATP2B2. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q9R0K7 |
antibody wiki: | |
SynGO gene info: | SynGO data @ ATP2B2 |
Ontology domain: | Cellular Component |
SynGO term: | presynaptic membrane (GO:0042734) |
Synapse type(s): | retina, glutamatergic Photoreceptor ribbon synapse |
Annotated paper: | Aartsen WM, et al. "PSD95beta regulates plasma membrane Ca2+ pump localization at the photoreceptor synapse" Mol Cell Neurosci. 2009 Jun;41(2):156-65 PMID:19233278 |
Figure(s): | FigS2 |
Annotation description: | FigS2 shows immunogold localization of PCMA2 in the presynaptic membrane in photoreceptor rod terminals. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
Additional literature: | Proteomic study of presynaptic active zone of rat. @ PMID:23622064 |
SynGO annotation ID: | 4088 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |