Annotated protein:Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2). Gene symbol: ATP2B2. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q9R0K7
antibody wiki:
SynGO gene info:SynGO data @ ATP2B2
Ontology domain:Cellular Component
SynGO term:presynaptic membrane (GO:0042734)
Synapse type(s):retina, glutamatergic
Photoreceptor ribbon synapse
Annotated paper:Aartsen WM, et al. "PSD95beta regulates plasma membrane Ca2+ pump localization at the photoreceptor synapse" Mol Cell Neurosci. 2009 Jun;41(2):156-65 PMID:19233278
Figure(s):FigS2
Annotation description:FigS2 shows immunogold localization of PCMA2 in the presynaptic membrane in photoreceptor rod terminals.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Daniela Dieterich (ORCID:0000-0002-9880-1214)
Rainer Pielot (ORCID:0000-0002-9681-3318)
Karl-Heinz Smalla (ORCID:0000-0002-0269-0311)
Eckart Gundelfinger (ORCID:0000-0001-9377-7414)
Lab:Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany
Additional literature:Proteomic study of presynaptic active zone of rat. @ PMID:23622064
SynGO annotation ID:4088
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology