| Annotated protein: | RCG36947 (Rap2A-like protein). Gene symbol: RAP2A. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q78P65 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ RAP2A |
| Ontology domain: | Cellular Component |
| SynGO term: | synapse (GO:0045202) |
| Synapse type(s): | forebrain |
| Annotated paper: | Kawabe H, et al. "Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development" Neuron. 2010 Feb 11;65(3):358-72 PMID:20159449 |
| Figure(s): | Fig. S1E |
| Annotation description: | Figure S1: Subcellular fractionation data from rat brain indicates that RAP2A is present in the PSD fraction. 11/01/2021 Dnyanada: RAP2A distribution is not limited to the PSD fraction but is also present in the synaptosomal (P2B), ER membrane/microsome (P2C), crude synaptic vesicle fraction (CSV) and crude synaptic membrane fraction (CSM). Based on this homogenous pattern of distribution in rat brain subcellular fractions, the generic term "synapse" was chosen. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Western blot Biochemical fractionation (generic) |
| Annotator(s): | Noa Lipstein (ORCID:0000-0002-0755-5899) Cordelia Imig (ORCID:0000-0001-7351-8706) Vincent O'connor (ORCID:0000-0003-3185-5709) Nils Brose (ORCID:0000-0003-0938-8534) |
| Lab: | Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany |
| SynGO annotation ID: | 3973 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |