Annotated protein:RCG36947 (Rap2A-like protein). Gene symbol: RAP2A. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q78P65
antibody wiki:
SynGO gene info:SynGO data @ RAP2A
Ontology domain:Cellular Component
SynGO term:synaptic membrane (GO:0097060)
Synapse type(s):forebrain
Annotated paper:Kawabe H, et al. "Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development" Neuron. 2010 Feb 11;65(3):358-72 PMID:20159449
Figure(s):Fig. S1F
Annotation description:Subcellular fractionation experiments indicate that RAP2A is present in the crude synaptic membrane fraction and the crude synaptic vesicle fraction, but not the synaptic soluble cytoplasm fraction.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Western blot
Biochemical fractionation (generic)
Annotator(s):Noa Lipstein (ORCID:0000-0002-0755-5899)
Cordelia Imig (ORCID:0000-0001-7351-8706)
Vincent O'connor (ORCID:0000-0003-3185-5709)
Nils Brose (ORCID:0000-0003-0938-8534)
Lab:Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany
SynGO annotation ID:3971
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology