Annotated protein: | AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma-adaptin 3b) (Sigma2-adaptin). Gene symbol: AP2S1. Taxonomy: Mus musculus (Mouse). Uniprot ID: P62743 |
antibody wiki: | |
SynGO gene info: | SynGO data @ AP2S1 |
Ontology domain: | Cellular Component |
SynGO term: | synapse (GO:0045202) |
Synapse type(s): | hippocampus |
Annotated paper: | Distler U, et al. "In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics" Proteomics. 2014 Nov;14(21-22):2607-13 PMID:25211037 |
Figure(s): | Supplementary Table 12 |
Annotation description: | The Table.S12 (tab 'other fractions') shows AP-2 complex subunit sigma; AP2S1 in multiple fractions. The maximum amount was found in the SJ fractions which is a 'synaptic junction' fraction. Term 'synapse' was selected accordingly. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | none of the above |
Evidence tracking, Experiment Assay: | Mass-spectrometry Biochemical fractionation (generic) |
Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 3937 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |