| Annotated protein: | AP-2 complex subunit mu (AP-2 mu chain) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein). Gene symbol: AP2M1. Taxonomy: Mus musculus (Mouse). Uniprot ID: P84091 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ AP2M1 |
| Ontology domain: | Cellular Component |
| SynGO term: | synapse (GO:0045202) |
| Synapse type(s): | hippocampus |
| Annotated paper: | Distler U, et al. "In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics" Proteomics. 2014 Nov;14(21-22):2607-13 PMID:25211037 |
| Figure(s): | Supplementary Table 12 |
| Annotation description: | The Table.S12 (tab 'other fractions') shows AP-2 complex subunit mu; AP2M1 in multiple fractions. The maximum amount was found in the SJ fractions which is a 'synaptic junction' fraction. Term 'synapse' was selected accordingly. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | none of the above |
| Evidence tracking, Experiment Assay: | Mass-spectrometry Biochemical fractionation (generic) |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 3935 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |