| Annotated protein: | Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (S6K) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA). Gene symbol: RPS6KB1. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q8BSK8 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ RPS6KB1 |
| Ontology domain: | Biological Process |
| SynGO term: | modulation of chemical synaptic transmission (GO:0050804) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Antion MD, et al. "Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity" Learn Mem. 2008 Jan 3;15(1):29-38 PMID:18174371 |
| Figure(s): | fig 7q |
| Annotation description: | S6K1 KO showed compromised early-phase LTP expression |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Genetic transformation (eg; knockout, knockin, mutations) |
| Evidence tracking, Experiment Assay: | Field recordings |
| Annotator(s): | Alexandros Kanellopoulos (ORCID:0000-0002-2094-7491) Vittoria Mariano (ORCID:0000-0002-9848-0262) Achsel Tilmann (ORCID:0000-0002-1190-4481) Claudia Bagni (ORCID:0000-0002-4419-210X) |
| Lab: | Department of Fundamental Neurosciences, University of Lausanne, CH-1006 Lausanne, Switzerland; Dept Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy |
| SynGO annotation ID: | 3923 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |