Annotated protein:Laminin subunit alpha-5 (Laminin-10 subunit alpha) (Laminin-11 subunit alpha) (Laminin-15 subunit alpha). Gene symbol: LAMA5. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q61001
antibody wiki:
SynGO gene info:SynGO data @ LAMA5
Ontology domain:Cellular Component
SynGO term:extracellular matrix of synaptic cleft (GO:0098965)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Omar MH, et al. "CNS Neurons Deposit Laminin alpha5 to Stabilize Synapses" Cell Rep. 2017 Oct 31;21(5):1281-1292 PMID:29091766
Figure(s):Fig.1
Annotation description:Fig.1: "Laminin α5 Is Deposited at Synapses by Hippocampal Neurons"
- "Hippocampal Neurons Deposit the ECM Protein Laminin α5 at Synapses"
- "Laminin α5 Is Delivered by the Postsynaptic Neuron"

9/7/2018 Pim
- Laminin is a known component of the ECM.
Evidence tracking, Biological System:Intact tissue
Cultured neurons
Evidence tracking, Protein Targeting:Over-expression
Antibody (detection)
Evidence tracking, Experiment Assay:Confocal
Western blot
Biochemical fractionation (generic)
Annotator(s):Pim van Nierop (ORCID:0000-0003-0593-3443)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:3842
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology