| Annotated protein: | Neuropilin and tolloid-like protein 2 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2). Gene symbol: NETO2. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q8BNJ6 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ NETO2 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic density membrane (GO:0099061) |
| Synapse type(s): | cerebellum, glutamatergic |
| Annotated paper: | Tang M, et al. "Neto2 interacts with the scaffolding protein GRIP and regulates synaptic abundance of kainate receptors" PLoS One. 2012;7(12):e51433 PMID:23236500 |
| Figure(s): | Fig.2 |
| Annotation description: | Fig.2: "KARs are reduced in the cerebellar PSD of Neto2-null mice." 9/7/2018 Pim - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Western blot Biochemical fractionation (generic) |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 3841 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |