| Annotated protein: | A-kinase anchor protein 1, mitochondrial (A-kinase anchor protein 121 kDa) (AKAP 121) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein 84) (S-AKAP84). Gene symbol: AKAP1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: O88884 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ AKAP1 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic specialization, intracellular component (GO:0099091) |
| Synapse type(s): | Neuro-muscular junction |
| Annotated paper: | Perkins GA, et al. "PKA, PKC, and AKAP localization in and around the neuromuscular junction" BMC Neurosci. 2001;2:17 PMID:11716788 |
| Figure(s): | Fig.3 |
| Annotation description: | "The distribution of D-AKAP1 at the postsynaptic NMJ and the adjacent muscle is similar to that of RIα, although there is no codistribution at the presynaptic region between these two labels (fig. (fig.3a).3a). D-AKAP1 is expressed in both NMJ and intercostal muscle. D-AKAP1 codistribution with cytochrome c (mitochondrial marker) is significant (fig. (fig.3a),3a)" |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 3814 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |