| Annotated protein: | Semaphorin-4B (Semaphorin-C) (Sema C). Gene symbol: SEMA4B. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q62179 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ SEMA4B |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic density membrane (GO:0099061) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Burkhardt C, et al. "Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif" FEBS Lett. 2005 Jul 4;579(17):3821-8 PMID:15978582 |
| Figure(s): | Fig.1, 3, 5 |
| Annotation description: | Fig.1: "PSD-95 interacts with class 4 semaphorins" Fig.3: "Co-expression of PSD-95 induces clustering of class 4 semaphorins in COS 7 cells" Fig.5: "Sema4B co-localizes with post-synaptic markers in hippocampal neurons" |
| Evidence tracking, Biological System: | Intact tissue Cultured neurons Non-neuronal tissue |
| Evidence tracking, Protein Targeting: | Over-expression Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal IP + WB/MSMS |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 3807 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |