Annotated protein:Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)]. Gene symbol: GPHN. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q8BUV3
antibody wiki:
SynGO gene info:SynGO data @ GPHN
Ontology domain:Cellular Component
SynGO term:postsynaptic specialization, intracellular component (GO:0099091)
Synapse type(s):olfactory bulb, GABAergic
Annotated paper:Panzanelli P, et al. "Early synapse formation in developing interneurons of the adult olfactory bulb" J Neurosci. 2009 Dec 2;29(48):15039-52 PMID:19955355
Figure(s):Fig. 1E-G; Fig. 9
Annotation description:Gephyrin at GABAergic postsynaptic density of mitral intrinsic profile receiving receiving to symmetric GABAergic inputs.
Preembedding electron microscopic immunohistochemistry on the olfactory bulb of GFP-GAD67 expressing mice.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Daniela Dieterich (ORCID:0000-0002-9880-1214)
Rainer Pielot (ORCID:0000-0002-9681-3318)
Karl-Heinz Smalla (ORCID:0000-0002-0269-0311)
Eckart Gundelfinger (ORCID:0000-0001-9377-7414)
Lab:Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany
Additional literature:Fig. 1E: GABAergic
Dissociated hippocampal neurons from Sprague-Dawley rats were cultured over glia (Lu et al., 1998) @ PMID:23982982
SynGO annotation ID:368
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology