Annotated protein: | Gephyrin (Putative glycine receptor-tubulin linker protein) [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)]. Gene symbol: GPHN. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q03555 |
antibody wiki: | |
SynGO gene info: | SynGO data @ GPHN |
Ontology domain: | Cellular Component |
SynGO term: | postsynaptic specialization, intracellular component (GO:0099091) |
Synapse type(s): | spinal cord, glycinergic |
Annotated paper: | Colin I, et al. "Localization of components of glycinergic synapses during rat spinal cord development" J Comp Neurol. 1998 Aug 31;398(3):359-72 PMID:9714149 |
Figure(s): | Fig. 5 |
Annotation description: | The figure documents postsynaptic localization of gephyrin immunoreactivity (nanogold) in glycinergic spinal cord synapses. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
Additional literature: | Localization of gephyrin immunorectivity (peroxidase) opposite glycine and GABA immunoreactivity in spinal cord. @ PMID:7711926 Localization of gephyrin immunorectivity (peroxidase) opposite glycine and GABA immunoreactivity in spinal cord. @ PMID:7642803 |
SynGO annotation ID: | 367 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |