| Annotated protein: | Small ribosomal subunit protein uS15 (40S ribosomal protein S13). Gene symbol: RPS13. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P62278 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ RPS13 |
| Ontology domain: | Cellular Component |
| SynGO term: | presynaptic ribosome |
| Annotated paper: | Peng J, et al. "Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry" J Biol Chem. 2004 May 14;279(20):21003-11 PMID:15020595 |
| Figure(s): | Table S1 |
| Annotation description: | 18/5/2018 Pim rule: NAS_CPLX_1 rationale: Ribosomes are present in the axonal compartment (Fig.1, RL22 used as marker protein using the RiboTag mouse line; electron and fluorescence microscopy) and protein translation is shown to occur in this compartment (PMID:27321671). RS13 is a generally accepted constituent of the ribosome. No functions of RS13 are known independent from the ribosomal complex. Inference to term "ribosome (GO:0005840)" part_of "presynapse (GO:0098793)" is trivial. C_ref CC: SynGO ID #1681 ("presynaptic ribosome") P_inf CC: SynGO ID #613 P_inf CC additional: - Bayes et al.(2012), PMID:23071613, TableS1, prep:psd - Distler et al.(2014), PMID:25211037, Table S1, prep:synapse Complex membership: RS13 protein is a fixed member of the 40S ribosomal subunit complex. - Shown in crystal structure (PMID:28138070, see Fig.1, name: us15) - GO annotations to "structural constituent of ribosome (GO:0003735)" (ISO and IEA) |
| Evidence tracking, Biological System: | |
| Evidence tracking, Protein Targeting: | |
| Evidence tracking, Experiment Assay: | |
| Non-tracable Author Statement (NAS): | This annotation required some inference over additional information/literature, and is not solely based on observations made in the annotated paper by its original authors. |
| Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
| Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
| Additional literature: | Fig. 2 demonstrates the localization of polyribosomes in the base, neck and head of spines. @ PMID:27321671 |
| SynGO annotation ID: | 3593 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |