Annotated protein: | Heterogeneous nuclear ribonucleoprotein M (hnRNP M) (M4 protein). Gene symbol: HNRNPM. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q62826 |
antibody wiki: | |
SynGO gene info: | SynGO data @ HNRNPM |
Ontology domain: | Biological Process |
SynGO term: | regulation of postsynapse organization (GO:0099175) |
Synapse type(s): | hippocampus, glutamatergic |
Annotated paper: | Zhang G, et al. "RNA binding proteins accumulate at the postsynaptic density with synaptic activity" J Neurosci. 2012 Jan 11;32(2):599-609 PMID:22238095 |
Figure(s): | Fig. 6 |
Annotation description: | Results: -Literal: We found that loss of hnRNPG and hnRNPM using two different shRNAs for each, results in differential changes in dendritic spine numbers." |
Evidence tracking, Biological System: | Cultured neurons |
Evidence tracking, Protein Targeting: | RNAi / shRNA |
Evidence tracking, Experiment Assay: | Wide-field fluorescence |
Annotator(s): | Rita Reig-Viader (ORCID:0000-0002-6893-6177) Àlex Bayés (ORCID:0000-0002-5265-6306) |
Lab: | Molecular Physiology of the Synapse Laboratory, Biomedical Research Institute Sant Pau, 08025 Barcelona, Spain and and Universitat Autnoma de Cerdanyola del Valls, Spain Barcelona, 08193 Bellaterra |
SynGO annotation ID: | 3108 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |