| Annotated protein: | Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase). Gene symbol: EEF2K. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P70531 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ EEF2K |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic density (GO:0014069) |
| Synapse type(s): | forebrain, glutamatergic |
| Annotated paper: | Asaki C, et al. "Localization of translational components at the ultramicroscopic level at postsynaptic sites of the rat brain" Brain Res. 2003 May 16;972(1-2):168-76 PMID:12711090 |
| Figure(s): | Fig.2d |
| Annotation description: | Eef2k is enriched in the PSD fraction. - " eEF2/CaMKIII was highly concentrated in the PSD fraction, while PDK was not detected in the PSD fraction but in the dendritic lipid raft and SPM fraction. " |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Western blot Biochemical fractionation (generic) |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 3055 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |