| Annotated protein: | Catechol O-methyltransferase (EC 2.1.1.6). Gene symbol: COMT. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P22734 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ COMT |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | neocortex, glutamatergic |
| Annotated paper: | Karhunen T, et al. "Catechol-O-methyltransferase (COMT) in rat brain: immunoelectron microscopic study with an antiserum against rat recombinant COMT protein" Neurosci Lett. 1995 Feb 24;187(1):57-60 PMID:7617303 |
| Figure(s): | Fig.1 |
| Annotation description: | Fig.1: " (e) COMT-ir in a postsynaptic dendritic spine (asterisk) in parietal cortex (at, axon terminal). (f) COMT-ir in a postsynaptic spine (asterisk) and in astrocytic processes (ap) in close association with an axon terminal (at) in parietal cortex." |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 3012 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |