| Annotated protein: | Non-muscle caldesmon (CDM) (L-caldesmon). Gene symbol: CALD1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q62736 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ CALD1 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Agassandian C, et al. "Subcellular distribution of calponin and caldesmon in rat hippocampus" Brain Res. 2000 Dec 29;887(2):444-9 PMID:11134639 |
| Figure(s): | Fig.2 |
| Annotation description: | Fig.2: "Calponin and caldesmon immunoreactivity are postsynaptic." - " (d) Cd-immunolabelling is present as patches in the dendritic shaft of hippocampal neurones and in the dendritic spines (Sp) that emerge from this dendrite (D). The immunoreactivity is particularly enriched by the cell membrane (small arrows), along the microtubules (arrowheads), between the sacks of the spine apparatus (large arrow) and in the post-synaptic density (white arrow)." |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| Additional literature: | Equivalent data in Amygdala @ PMID:18582438 |
| SynGO annotation ID: | 3009 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |