| Annotated protein: | Clathrin light chain A (Lca). Gene symbol: CLTA. Taxonomy: Mus musculus (Mouse). Uniprot ID: O08585 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ CLTA |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic endocytic zone (GO:0098843) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Lu J, et al. "Postsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to Homer" Neuron. 2007 Sep 20;55(6):874-89 PMID:17880892 |
| Figure(s): | Fig.1 |
| Annotation description: | Fig.1: "The Endocytic Zone is Stably Positioned Near the PSD" 13/3/2018 Pim - CLTA; clathrin light chain A is used as a marker for Endocytic Zones (EZ's). These are shown to be close to and physically attached to the PSD via the homer and dynamin-3 proteins. |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Over-expression |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 2878 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |