| Annotated protein: | Protein Wnt-3a. Gene symbol: WNT3A. Taxonomy: Homo sapiens (Human). Uniprot ID: P56704 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ WNT3A |
| Ontology domain: | Biological Process |
| SynGO term: | regulation of presynapse assembly (GO:1905606) |
| Synapse type(s): | hippocampus |
| Annotated paper: | Varela-Nallar L, et al. "Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function" Neural Dev. 2009 Nov 2;4:41 PMID:19883499 |
| Figure(s): | Fig.5, 6 |
| Annotation description: | Fig.5: "Wnt-3a induces presynaptic differentiation in cultured hippocampal neurons mediated by the Fz1 receptor." [Fig.6: "Wnt-3a stimulates synaptic vesicle release in mature cultured hippocampal neurons"] |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Over-expression |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 2801 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |