| Annotated protein: | Netrin-G2 (Laminet-2). Gene symbol: NTNG2. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q8R4F1 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ NTNG2 |
| Ontology domain: | Biological Process |
| SynGO term: | regulation of presynapse assembly (GO:1905606) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Kim S, et al. "NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation" Nat Neurosci. 2006 Oct;9(10):1294-301 PMID:16980967 |
| Figure(s): | fig 4, 5 |
| Annotation description: | Note: Netrin-G2; NTNG2 is a postsynaptic protein. Fig.4: "NGL-2 expression in heterologous cells induces functional presynaptic differentiation in contacting neurites." Fig.5: "Beads bearing the ectodomain of NGL-2 induce functional excitatory presynaptic differentiation in contacting neurites" |
| Evidence tracking, Biological System: | Cultured neurons Non-neuronal tissue |
| Evidence tracking, Protein Targeting: | Over-expression |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
| Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
| SynGO annotation ID: | 2764 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |