| Annotated protein: | Semaphorin-3F (Semaphorin IV) (Sema IV). Gene symbol: SEMA3F. Taxonomy: Mus musculus (Mouse). Uniprot ID: O88632 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ SEMA3F |
| Ontology domain: | Biological Process |
| SynGO term: | regulation of postsynapse organization (GO:0099175) |
| Synapse type(s): | cerebral cortex, glutamatergic |
| Annotated paper: | Demyanenko GP, et al. "Neural cell adhesion molecule NrCAM regulates Semaphorin 3F-induced dendritic spine remodeling" J Neurosci. 2014 Aug 20;34(34):11274-87 PMID:25143608 |
| Figure(s): | fig 6, 7 |
| Annotation description: | Fig.6: "NrCAM regulates Sema3F-induced spine retraction of cortical neurons" Fig.7: "Sema3F and NrCAM genetically interact to regulate spine density" |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Genetic transformation (eg; knockout, knockin, mutations) Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy Confocal Whole-cell patch clamp |
| Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
| Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
| SynGO annotation ID: | 2762 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |