| Annotated protein: | SLIT and NTRK-like family, member 2. Gene symbol: SLITRK2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: D3ZK41 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ SLITRK2 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic membrane (GO:0099055) |
| Synapse type(s): | brain |
| Annotated paper: | Yim YS, et al. "Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases" Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4057-62 PMID:23345436 |
| Figure(s): | fig 1E |
| Annotation description: | SLITRK2 was detected, although not enriched, in PSDI and PSDII fractions. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Western blot Biochemical fractionation (generic) |
| Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
| Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
| Additional literature: | Crystal structure of SLITRK2 and PTPRD, which together with presynaptic localization of PTPRD and postsynaptic localization of SLITRK2, supports a trans-synaptic adhesion between the two proteins. @ PMID:25989451 |
| SynGO annotation ID: | 2699 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |