Annotated protein: | SLIT and NTRK-like family, member 1. Gene symbol: SLITRK1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: D3Z8D8 |
antibody wiki: | |
SynGO gene info: | SynGO data @ SLITRK1 |
Ontology domain: | Cellular Component |
SynGO term: | integral component of postsynaptic density membrane (GO:0099061) |
Synapse type(s): | brain |
Annotated paper: | Yim YS, et al. "Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases" Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4057-62 PMID:23345436 |
Figure(s): | fig 1E |
Annotation description: | SLITRK1 was enriched in PSD fractions up to PSDIII, which is highly detergent-resistant. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Western blot Biochemical fractionation (generic) |
Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
Additional literature: | SLITRK1 is co-localized with VGLUT1/PSD-95, but not with VGAT/Gephyrin and enriched postsynaptic density fractions. @ PMID:27273464 |
SynGO annotation ID: | 2698 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |