Annotated protein:SLIT and NTRK-like family, member 1. Gene symbol: SLITRK1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: D3Z8D8
antibody wiki:
SynGO gene info:SynGO data @ SLITRK1
Ontology domain:Cellular Component
SynGO term:integral component of postsynaptic density membrane (GO:0099061)
Synapse type(s):brain
Annotated paper:Yim YS, et al. "Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases" Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4057-62 PMID:23345436
Figure(s):fig 1E
Annotation description:SLITRK1 was enriched in PSD fractions up to PSDIII, which is highly detergent-resistant.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Western blot
Biochemical fractionation (generic)
Annotator(s):Hwajin Jung (ORCID:0000-0001-6194-9648)
Eunjoon Kim (ORCID:0000-0001-5518-6584)
Lab:Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea
Additional literature:SLITRK1 is co-localized with VGLUT1/PSD-95, but not with VGAT/Gephyrin and enriched postsynaptic density fractions. @ PMID:27273464
SynGO annotation ID:2698
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology