| Annotated protein: | von Hippel-Lindau disease tumor suppressor (pVHL). Gene symbol: VHL. Taxonomy: Mus musculus (Mouse). Uniprot ID: P40338 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ VHL |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic density (GO:0014069) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Segura I, et al. "The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A" Cell Rep. 2016 Mar 22;14(11):2653-67 PMID:26972007 |
| Figure(s): | Fig.4, 5, 6, 7, Suppl.Fig.9 |
| Annotation description: | Fig.4: - "FLNA Is Expressed in Dendritic Filopodia and Spines" - "FLNA Is Stabilized by Hypoxia, DMOG, or PHD2 Knockdown" - Note: VHL is present in PSD (Fig.4C) |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Western blot Biochemical fractionation (generic) |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 2671 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |