| Annotated protein: | Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48). Gene symbol: PTPRD. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q64487 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ PTPRD |
| Ontology domain: | Biological Process |
| SynGO term: | modulation of chemical synaptic transmission (GO:0050804) |
| Synapse type(s): | Schaffer collateral synapse (CA3->CA1) Mossy fiber synapse (DG->CA3) |
| Annotated paper: | Uetani N, et al. "Impaired learning with enhanced hippocampal long-term potentiation in PTPdelta-deficient mice" EMBO J. 2000 Jun 15;19(12):2775-85 PMID:10856223 |
| Figure(s): | fig 6G-H |
| Annotation description: | LTP induction was enhanced in PTPRD KO mice. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Genetic transformation (eg; knockout, knockin, mutations) |
| Evidence tracking, Experiment Assay: | Field recordings |
| Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
| Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
| SynGO annotation ID: | 2648 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |