Annotated protein: | Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56). Gene symbol: NCAM1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P13596 |
antibody wiki: | |
SynGO gene info: | SynGO data @ NCAM1 |
Ontology domain: | Biological Process |
SynGO term: | modulation of chemical synaptic transmission (GO:0050804) |
Synapse type(s): | Schaffer collateral synapse (CA3->CA1) |
Annotated paper: | Luthi A, et al. "Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM" Nature. 1994 Dec 22-29;372(6508):777-9 PMID:7997264 |
Figure(s): | fig 2 |
Annotation description: | NCAM antibodies and NCAM fragments blocks TBS-induced LTP. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Over-expression Antibody (detection) |
Evidence tracking, Experiment Assay: | Field recordings |
Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
SynGO annotation ID: | 2642 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |