Annotated protein:Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56). Gene symbol: NCAM1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P13596
antibody wiki:
SynGO gene info:SynGO data @ NCAM1
Ontology domain:Biological Process
SynGO term:modulation of chemical synaptic transmission (GO:0050804)
Synapse type(s):Schaffer collateral synapse (CA3->CA1)
Annotated paper:Luthi A, et al. "Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM" Nature. 1994 Dec 22-29;372(6508):777-9 PMID:7997264
Figure(s):fig 2
Annotation description:NCAM antibodies and NCAM fragments blocks TBS-induced LTP.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Over-expression
Antibody (detection)
Evidence tracking, Experiment Assay:Field recordings
Annotator(s):Hwajin Jung (ORCID:0000-0001-6194-9648)
Eunjoon Kim (ORCID:0000-0001-5518-6584)
Lab:Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea
SynGO annotation ID:2642
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology