| Annotated protein: | Flotillin-2 (Reggie-1) (REG-1). Gene symbol: FLOT2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q9Z2S9 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ FLOT2 |
| Ontology domain: | Cellular Component |
| SynGO term: | synapse (GO:0045202) |
| Synapse type(s): | brain |
| Annotated paper: | Suzuki T, et al. "Association of membrane rafts and postsynaptic density: proteomics, biochemical, and ultrastructural analyses" J Neurochem. 2011 Oct;119(1):64-77 PMID:21797867 |
| Figure(s): | Suppl. Table 1, Fig. 4 |
| Annotation description: | Flotillin-2 is found in synaptic proteomes (in detergent-resistant membranes associated to postsynaptic density preparations). It seems to be present in both pre- (SynGO-ID 260) and postsynaptically. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Western blot Mass-spectrometry Biochemical fractionation (generic) |
| Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
| Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
| Additional literature: | Collins MO, Husi H, Yu L, Brandon JM, Anderson CN, Blackstock WP, Choudhary JS, Grant SG. Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome. J Neurochem. 2006 Apr;97 Suppl 1:16-23. @ PMID:16635246 |
| SynGO annotation ID: | 263 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |