Annotated protein: | SLIT and NTRK-like protein 2. Gene symbol: SLITRK2. Taxonomy: Homo sapiens (Human). Uniprot ID: Q9H156 |
antibody wiki: | |
SynGO gene info: | SynGO data @ SLITRK2 |
Ontology domain: | Biological Process |
SynGO term: | regulation of synapse organization (GO:0050807) |
Synapse type(s): | hippocampus, glutamatergic hippocampus, GABAergic |
Annotated paper: | Beaubien F, et al. "Slitrk1 is localized to excitatory synapses and promotes their development" Sci Rep. 2016 Jun 7;6:27343 PMID:27273464 |
Figure(s): | Fig.2 |
Annotation description: | Fig.2: "Overexpression of Slitrk1 and Slitrk2 in cultured neurons increases the amount of presynaptic excitatory and inhibitory contacts" |
Evidence tracking, Biological System: | Cultured neurons |
Evidence tracking, Protein Targeting: | Over-expression |
Evidence tracking, Experiment Assay: | Confocal |
Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 2620 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |