Annotated protein:SLIT and NTRK-like protein 2. Gene symbol: SLITRK2. Taxonomy: Homo sapiens (Human). Uniprot ID: Q9H156
antibody wiki:
SynGO gene info:SynGO data @ SLITRK2
Ontology domain:Biological Process
SynGO term:regulation of synapse organization (GO:0050807)
Synapse type(s):hippocampus, glutamatergic
hippocampus, GABAergic
Annotated paper:Beaubien F, et al. "Slitrk1 is localized to excitatory synapses and promotes their development" Sci Rep. 2016 Jun 7;6:27343 PMID:27273464
Figure(s):Fig.2
Annotation description:Fig.2: "Overexpression of Slitrk1 and Slitrk2 in cultured neurons increases the amount of presynaptic excitatory and inhibitory contacts"
Evidence tracking, Biological System:Cultured neurons
Evidence tracking, Protein Targeting:Over-expression
Evidence tracking, Experiment Assay:Confocal
Annotator(s):Pim van Nierop (ORCID:0000-0003-0593-3443)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:2620
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology