| Annotated protein: | Integrin beta-1 (Fibronectin receptor subunit beta) (VLA-4 subunit beta) (CD antigen CD29). Gene symbol: ITGB1. Taxonomy: Mus musculus (Mouse). Uniprot ID: P09055 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ ITGB1 |
| Ontology domain: | Biological Process |
| SynGO term: | modulation of chemical synaptic transmission (GO:0050804) |
| Synapse type(s): | Schaffer collateral synapse (CA3->CA1) |
| Annotated paper: | Huang Z, et al. "Distinct roles of the beta 1-class integrins at the developing and the mature hippocampal excitatory synapse" J Neurosci. 2006 Oct 25;26(43):11208-19 PMID:17065460 |
| Figure(s): | fig 6, 9 |
| Annotation description: | Impairment of LTP but not basal transmission in the hippocampus of ITGB1/Emx1-cre mice. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Genetic transformation (eg; knockout, knockin, mutations) |
| Evidence tracking, Experiment Assay: | Field recordings |
| Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
| Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
| SynGO annotation ID: | 2602 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |