| Annotated protein: | Diacylglycerol kinase beta (DAG kinase beta) (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta). Gene symbol: DGKB. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q6NS52 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ DGKB |
| Ontology domain: | Biological Process |
| SynGO term: | modulation of chemical synaptic transmission (GO:0050804) |
| Synapse type(s): | hippocampus Schaffer collateral synapse (CA3->CA1) |
| Annotated paper: | Shirai Y, et al. "Essential role of neuron-enriched diacylglycerol kinase (DGK), DGKbeta in neurite spine formation, contributing to cognitive function" PLoS One. 2010 Jul 15;5(7):e11602 PMID:20657643 |
| Figure(s): | fig 3 |
| Annotation description: | Impaired long-term potentiation (LTP) in DGKB KO mice. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Genetic transformation (eg; knockout, knockin, mutations) |
| Evidence tracking, Experiment Assay: | Field recordings |
| Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
| Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
| SynGO annotation ID: | 2597 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |