| Annotated protein: | Synaptotagmin-11 (Synaptotagmin XI) (SytXI). Gene symbol: SYT11. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: O08835 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ SYT11 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of synaptic vesicle membrane (GO:0030285) |
| Synapse type(s): | Schaffer collateral synapse (CA3->CA1) |
| Annotated paper: | Yeo H, et al. "Developmental expression and subcellular distribution of synaptotagmin 11 in rat hippocampus" Neuroscience. 2012 Dec 6;225:35-43 PMID:22960622 |
| Figure(s): | Fig. 6 |
| Annotation description: | Results section. "Ultrastructural localization of Syt11 in rat hippocampal CA1 synapses by immunoelectron microscopy" -Literal: " We finally examined the ultrastructural distribution of Syt11 protein in rat hippocampus by immunogold EM (Fig. 6) ...In axon terminals, Syt11 signals were colocalized with presynaptic vesicles..." 22/2/2018 Pim - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Rita Reig-Viader (ORCID:0000-0002-6893-6177) Àlex Bayés (ORCID:0000-0002-5265-6306) |
| Lab: | Molecular Physiology of the Synapse Laboratory, Biomedical Research Institute Sant Pau, 08025 Barcelona, Spain and and Universitat Autnoma de Cerdanyola del Valls, Spain Barcelona, 08193 Bellaterra |
| SynGO annotation ID: | 2565 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |