| Annotated protein: | Ephrin type-B receptor 2 (EC 2.7.10.1) (Neural kinase) (Nuk receptor tyrosine kinase) (Tyrosine-protein kinase receptor EPH-3) (Tyrosine-protein kinase receptor SEK-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]. Gene symbol: EPHB2. Taxonomy: Mus musculus (Mouse). Uniprot ID: P54763 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ EPHB2 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic membrane (GO:0099055) |
| Synapse type(s): | hippocampus, glutamatergic neocortex, glutamatergic thalamus |
| Annotated paper: | Bouvier D, et al. "Pre-synaptic and post-synaptic localization of EphA4 and EphB2 in adult mouse forebrain" J Neurochem. 2008 Jul;106(2):682-95 PMID:18410519 |
| Figure(s): | fig 2, 4, 5, 6, 7, and 8. table 1 |
| Annotation description: | EphB2 shows weak interaction with PSD fraction (Fig.2). EphB2 is predominantly present in the plasma membrane of dendritic spine shafts in hippocampus (Fig.4/5/6) and thalamus (Fig.7/8). The data point justifies term "integral component of postsynaptic membrane (GO:0099055) |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy Western blot Biochemical fractionation (generic) |
| Annotator(s): | Tony Cijsouw (ORCID:0000-0003-0912-1514) Thomas Biederer (ORCID:0000-0002-3670-7863) |
| Lab: | Department of Neuroscience, Tufts University School of Medicine, Boston, MA 02111, USA |
| SynGO annotation ID: | 256 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |