Annotated protein:Epsin-1 (EPS-15-interacting protein 1). Gene symbol: EPN1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: O88339
antibody wiki:
SynGO gene info:SynGO data @ EPN1
Ontology domain:Cellular Component
SynGO term:postsynapse (GO:0098794)
Synapse type(s):Schaffer collateral synapse (CA3->CA1)
Annotated paper:Yao PJ, et al. "Partially overlapping distribution of epsin1 and HIP1 at the synapse: analysis by immunoelectron microscopy" J Comp Neurol. 2006 Jan 10;494(2):368-79 PMID:16320245
Figure(s):Fig. 2, 4, 6
Annotation description:The authors use immuno gold EM with well characterized epsin 1 antibody. Direct quote from the legend to figure 2 "In the postsynaptic compartment, the epsin 1 immunolabeling was found in various locations, some near the postsynaptic density (Fig. 2D,E,G) but other scattered throughout the cytoplasm (Fig. 2F)".
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Peter McPherson (ORCID:0000-0001-7806-5662)
Lab:Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada
SynGO annotation ID:2538
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology