Annotated protein:D(1B) dopamine receptor (D(5) dopamine receptor) (Dopamine D5 receptor). Gene symbol: DRD5. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P25115
antibody wiki:
SynGO gene info:SynGO data @ DRD5
Ontology domain:Cellular Component
SynGO term:integral component of postsynaptic density membrane (GO:0099061)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Medin T, et al. "Dopamine D5 receptors are localized at asymmetric synapses in the rat hippocampus" Neuroscience. 2011 Sep 29;192:164-71 PMID:21749912
Figure(s):Fig.3, 4
Annotation description:Fig.3: " Within the spines, labelling was most commonly observed over the postsynaptic membrane overlying the PSD, although some labelling was present in the spine neck and perisynaptically (data not shown)."
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Pim van Nierop (ORCID:0000-0003-0593-3443)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:2532
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology