Annotated protein: | D(1B) dopamine receptor (D(5) dopamine receptor) (Dopamine D5 receptor). Gene symbol: DRD5. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P25115 |
antibody wiki: | |
SynGO gene info: | SynGO data @ DRD5 |
Ontology domain: | Cellular Component |
SynGO term: | integral component of postsynaptic density membrane (GO:0099061) |
Synapse type(s): | hippocampus, glutamatergic |
Annotated paper: | Medin T, et al. "Dopamine D5 receptors are localized at asymmetric synapses in the rat hippocampus" Neuroscience. 2011 Sep 29;192:164-71 PMID:21749912 |
Figure(s): | Fig.3, 4 |
Annotation description: | Fig.3: " Within the spines, labelling was most commonly observed over the postsynaptic membrane overlying the PSD, although some labelling was present in the spine neck and perisynaptically (data not shown)." |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 2532 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |