Annotated protein:Leucine-rich repeat-containing protein 4C (Netrin-G1 ligand) (NGL-1). Gene symbol: LRRC4C. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q8C031
antibody wiki:
SynGO gene info:SynGO data @ LRRC4C
Ontology domain:Biological Process
SynGO term:modulation of chemical synaptic transmission (GO:0050804)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Matsukawa H, et al. "Netrin-G/NGL complexes encode functional synaptic diversification" J Neurosci. 2014 Nov 19;34(47):15779-92 PMID:25411505
Figure(s):fig 6E
Annotation description:LRRC4C KO mice showed impaired post-tetanic depression (PTD) in hippocampus MPP-DG pathway.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Genetic transformation (eg; knockout, knockin, mutations)
Evidence tracking, Experiment Assay:Field recordings
Annotator(s):Hwajin Jung (ORCID:0000-0001-6194-9648)
Eunjoon Kim (ORCID:0000-0001-5518-6584)
Lab:Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea
SynGO annotation ID:2403
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology