Annotated protein:Catenin delta 1. Gene symbol: CTNND1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: D3ZZZ9
antibody wiki:
SynGO gene info:SynGO data @ CTNND1
Ontology domain:Cellular Component
SynGO term:postsynaptic density, intracellular component (GO:0099092)
Synapse type(s):hippocampus, glutamatergic
cerebellum, glutamatergic
Schaffer collateral synapse (CA3->CA1)
Mossy fiber synapse (DG->CA3)
Annotated paper:Chauvet N, et al. "Distribution of p120 catenin during rat brain development: potential role in regulation of cadherin-mediated adhesion and actin cytoskeleton organization" Mol Cell Neurosci. 2003 Apr;22(4):467-86 PMID:12727444
Figure(s):Figure 8, 9A, B
Annotation description:Electron microscopy of the CA1 and CA3 regions using peroxidase-based staining of catenin delta/p120catenin, indicates expression in the presynaptic compartment, associated with the active zone region.

Antibody info: 'Two monoclonal anti- bodies (mAbs) raised against p120ctn were used. mAb pp120 has been raised against p120ctn carboxyl-terminal amino acids 790-911 and recognizes all known p120ctn isoforms. mAb 6H11 was raised against the amino-terminal region of p120ctn, amino acids 8-349, and recognizes spe- cifically isoforms 1 and 2 of p120ctn'.
Evidence tracking, Biological System:Intact tissue
Cultured neurons
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Confocal
Annotator(s):Noa Lipstein (ORCID:0000-0002-0755-5899)
Cordelia Imig (ORCID:0000-0001-7351-8706)
Vincent O'connor (ORCID:0000-0003-3185-5709)
Nils Brose (ORCID:0000-0003-0938-8534)
Lab:Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany
SynGO annotation ID:2372
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology