| Annotated protein: | Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48) (3F8 chondroitin sulfate proteoglycan) (3H1 keratan sulfate proteoglycan) (Phosphacan). Gene symbol: PTPRZ1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q62656 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ PTPRZ1 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic density membrane (GO:0099061) |
| Synapse type(s): | hippocampus, glutamatergic neocortex, glutamatergic |
| Annotated paper: | Hayashi N, et al. "Synaptic localization of receptor-type protein tyrosine phosphatase zeta/beta in the cerebral and hippocampal neurons of adult rats" Brain Res. 2005 Jul 19;1050(1-2):163-9 PMID:15982644 |
| Figure(s): | fig 3, fig 4 |
| Annotation description: | Immunoreactivity of RPTPZ1 with electron-dense deposits was seen at the postsynaptic membrane of dendritic shaft but not presynaptic terminals. 26/01/2018 Pim - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
| Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
| SynGO annotation ID: | 2313 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |