| Annotated protein: | Neuroplastin (Glycoprotein 55/65) (gp55/65) (Stromal cell-derived receptor 1) (SDR-1). Gene symbol: NPTN. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P97546 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ NPTN |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic density membrane (GO:0099061) |
| Synapse type(s): | forebrain |
| Annotated paper: | Hill IE, et al. "Characterization of novel glycoprotein components of synaptic membranes and postsynaptic densities, gp65 and gp55, with a monoclonal antibody" Brain Res. 1988 Sep 27;461(1):27-43 PMID:3224275 |
| Figure(s): | fig. 3, table 1 |
| Annotation description: | first description as a synaptic protein with weak evidence based purely on enrichment with PSD fraction (detergent-resistant synaptic protein preparation; Pielot et al., 2012), semiquantitative WB 5/12/2016 Pim: - integral component in the annotation is derived from TM-domains in the annotated protein. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Western blot Biochemical fractionation (generic) |
| Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
| Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
| SynGO annotation ID: | 23 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |