Annotated protein: | Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO). Gene symbol: CORO1A. Taxonomy: Mus musculus (Mouse). Uniprot ID: O89053 |
antibody wiki: | |
SynGO gene info: | SynGO data @ CORO1A |
Ontology domain: | Cellular Component |
SynGO term: | synapse (GO:0045202) |
Synapse type(s): | hippocampus, glutamatergic |
Annotated paper: | Jayachandran R, et al. "Coronin 1 regulates cognition and behavior through modulation of cAMP/protein kinase A signaling" PLoS Biol. 2014 Mar 25;12(3):e1001820 PMID:24667537 |
Figure(s): | Fig.2 |
Annotation description: | Fig.2: "Coronin 1 distribution and localization in excitatory and inhibitory neurons" - Literal: "Coronin 1 was highly enriched in synapses, as judged by the extensive colocalization with synapsin 1 (Figure 2G) [36]. Together, these results suggest that coronin 1 is enriched at excitatory synapses." 15/01/2018 Pim - Coronin-1A gene not mentioned in the paper (referred to as 'Coronin-1') but can be derived from the genomic localization of the gene (chromosome 16) mentioned in the paper. |
Evidence tracking, Biological System: | Cultured neurons |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Confocal |
Annotator(s): | Rita Reig-Viader (ORCID:0000-0002-6893-6177) Àlex Bayés (ORCID:0000-0002-5265-6306) |
Lab: | Molecular Physiology of the Synapse Laboratory, Biomedical Research Institute Sant Pau, 08025 Barcelona, Spain and and Universitat Autnoma de Cerdanyola del Valls, Spain Barcelona, 08193 Bellaterra |
SynGO annotation ID: | 2294 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |