Annotated protein: | Gamma-aminobutyric acid receptor subunit delta (GABA(A) receptor subunit delta). Gene symbol: GABRD. Taxonomy: Mus musculus (Mouse). Uniprot ID: P22933 |
antibody wiki: | |
SynGO gene info: | SynGO data @ GABRD |
Ontology domain: | Cellular Component |
SynGO term: | integral component of postsynaptic membrane (GO:0099055) |
Synapse type(s): | hippocampus, GABAergic |
Annotated paper: | Wei W, et al. "Perisynaptic localization of delta subunit-containing GABA(A) receptors and their activation by GABA spillover in the mouse dentate gyrus" J Neurosci. 2003 Nov 19;23(33):10650-61 PMID:14627650 |
Figure(s): | Fig.2 |
Annotation description: | Fig.2: "Immunogold labeling of the δ and α2 subunits of the GABAA receptor. Gold particles that indicate the location of the δ subunit (A-D, arrows) were present on or near the plasma membrane of dendrites (D) that were in contact with axon terminals (T). Gold particles were localized primarily at perisynaptic sites, just outside or at the outer edge of symmetric synapses (A, D, solid arrowheads)." |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 2261 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |