| Annotated protein: | Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56). Gene symbol: NCAM1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P13596 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ NCAM1 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of presynaptic membrane (GO:0099056) |
| Synapse type(s): | caudateputamen, glutamatergic |
| Annotated paper: | DiFiglia M, et al. "Ultrastructural localization of molecular subtypes of immunoreactive neural cell adhesion molecule (NCAM) in the adult rodent striatum" J Neurosci. 1989 Dec;9(12):4158-68 PMID:2592994 |
| Figure(s): | fig 6 |
| Annotation description: | An NCAM-positive terminal emerges from a preterminal axon that is also NCAM immunoreactive and forms a synapse with a spine. 6/2/2018 PIm - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
| Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
| Additional literature: | N-CAM antibodies stained all surface membranes including pre- and postsynaptic membranes. @ PMID:2794140 |
| SynGO annotation ID: | 2224 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |