| Annotated protein: | Leucine-rich repeat and fibronectin type-III domain-containing protein 5. Gene symbol: LRFN5. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: D4A1J9 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ LRFN5 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic density membrane (GO:0099061) |
| Synapse type(s): | brain |
| Annotated paper: | Mah W, et al. "Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation" J Neurosci. 2010 Apr 21;30(16):5559-68 PMID:20410109 |
| Figure(s): | fig 4D/H |
| Annotation description: | LRFN5 was enriched in postsynaptic density fractions. 15/01/2018 Pim - LRFN5 displays a (low affinity) interaction with the PSD-95 protein (Fig.4H) - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Western blot Biochemical fractionation (generic) IP + WB/MSMS |
| Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
| Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
| SynGO annotation ID: | 2216 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |