Annotated protein:Leucine-rich repeat and fibronectin type-III domain-containing protein 4. Gene symbol: LRFN4. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: D4ABX8
antibody wiki:
SynGO gene info:SynGO data @ LRFN4
Ontology domain:Cellular Component
SynGO term:integral component of postsynaptic density membrane (GO:0099061)
Synapse type(s):brain
Annotated paper:Mah W, et al. "Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation" J Neurosci. 2010 Apr 21;30(16):5559-68 PMID:20410109
Figure(s):fig 4D/F/G
Annotation description:LRFN4 was enriched in postsynaptic density fractions.

15/01/2018 Pim
- LRFN4 displays an interaction with the PSD-95 protein (Fig.4F/G)
- Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Western blot
Biochemical fractionation (generic)
Annotator(s):Hwajin Jung (ORCID:0000-0001-6194-9648)
Eunjoon Kim (ORCID:0000-0001-5518-6584)
Lab:Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea
SynGO annotation ID:2215
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology